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产品目录

重组小鼠DR6(TNFRSF21)图片
产品货号:
JN0465
中文名称:
重组小鼠DR6(TNFRSF21)
英文名称:
Recombinant Mouse Death Receptor 6
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln42-His349在C端含有Fc标签和His标签

DR6/TNFRSF21质量控制:>95%(还原性SDS-PAGE)

DR6/TNFRSF21制剂:冻干品

DR6/TNFRSF21保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

DR6/TNFRSF21复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于DR6/TNFRSF21
Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may activate JNK and be involved in T-cell differentiation.It is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
相关搜索:重组小鼠DR6(TNFRSF21)Recombinant Mouse Death Receptor 6
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